Research at the Institute of Tissue Medicine and Pathology deals with the development, diagnosis and treatment of diseases. Immune pathologies, inflammatory diseases and tumor biology are the current research interests. Ex vivo studies of human tissue samples and the use of experimental in vitro and in vivo model systems are used to answer our research questions.
Treatment of the chronic inflammatory bowel disease ulcerative colitis often produces unsatisfactory results. Researchers at the University of Bern have now developed a lipid gel that is administered directly to the inflamed part of the intestine, where it remains and releases its active substance evenly. This could result in a new, targeted therapy approach with fewer side effects.
Photos 4_20231024_UniBE_Figure ©University_of_Bern_Martina_Carone:png
Blood poisoning caused by a fungal infection is a severe, life-threatening condition. Researchers at the University of Bern have now discovered a mechanism that helps a yeast fungus to spread more easily within the body. The immune system, of all things, plays a major role in this process. These findings could open up new therapeutic avenues for blood poisoning caused by yeast, but also for other invasive fungal infections.
Group Freigang, 2023/08/31
Sometimes doctors discover a rare tumour when they examine the excised tissue after an appendectomy. If the tumour has already reached a diameter of almost two centimetres, it was previously recommended to remove the adjacent part of the colon. But this should be avoided, as researchers in Bern have shown with a careful evaluation of tissue samples and clinical data from all over Europe.
Publication of the Swiss Cancer Research Foundation and the Swiss Cancer League