Institute of Tissue Medicine and Pathology

WELCOME TO THE INSTITUTE OF TISSUE MEDICINE AND PATHOLOGY, UNIVERSITY BERN

The Institute of Tissue Medicine and Pathology covers the entire width of the morphological and molecular diagnostics of tissue samples.

The combination of service, teaching and research under one roof allows for close interaction and mutual inspiration.

Opening hours Mo - Fr, 7:45 - 17:30 h

Important phone numbers

Media Releases

Research

How fungal infections cause blood poisoning

Blood poisoning caused by a fungal infection is a severe, life-threatening condition. Researchers at the University of Bern have now discovered a mechanism that helps a yeast fungus to spread more easily within the body. The immune system, of all things, plays a major role in this process. These findings could open up new therapeutic avenues for blood poisoning caused by yeast, but also for other invasive fungal infections.

Group Freigang, 2023/08/31

Annual report

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Research

Avoid unnecessary surgeries

Sometimes doctors discover a rare tumour when they examine the excised tissue after an appendectomy. If the tumour has already reached a diameter of almost two centimetres, it was previously recommended to remove the adjacent part of the colon. But this should be avoided, as researchers in Bern have shown with a careful evaluation of tissue samples and clinical data from all over Europe.

Publication of the Swiss Cancer Research Foundation and the Swiss Cancer League

Awards/Honours

Philipp Zens received the Best Poster Award in the category of pathology/tumor biology during the European Lung Cancer Congress 2023 in Copenhagen. The presented results are the next pieces of the multicentric project (collaboration with Sabina Berezowska, CHUV) focusing on the molecular characterization of paired primary lung carcinoma and brain metastases. In concordance to the genomic characterization the MAPK-pathway popped up as the most differentially methylated pathway. Additionally, we could cluster the cohort in a brain metastasis specific, primary lung cancer specific and mixed group of samples.

Forschung

Berner Studie wird Übertherapie bei NET des Blinddarms verhindern

Mit Evidenz zu einer Verbesserung der Behandlung! Internationale Studie unter Leitung der endokrinen Chirurgie des Inselspitals und unseres Institutes stellt ein Dogma in Frage: Entgegen der bisherigen Annahme sind mikroskopische Ableger in Lymphdrüsen von neuroendokrinen Tumoren des Blinddarm-Wurmfortsatzes für den Patienten nicht wichtig. Deshalb muss der Dickdarm nicht entfernt werden.

News

Annual Report 2022

Our new annual report is online now.

Bern led international study will reduce overtherapy in appendiceal NET

Evidence leads to improved patient treatment! An international study led by endocrine surgery of the Inselspital and our Institute challanges a dogma: Contrary to the current concept seem microscopic lymph node metastases of appendiceal NET irrelevant for patients. Therefore there is no indication for right sided hemicolectomy.

Renewal of the accreditation as testing laboratory for pathological diagnostics

We are glad to announce the renewal of the accreditation. Starting 29.11.2022 our institute is accredited by the Swiss Accreditation Service (SAS) according to the standard ISO 15189:2012 and the Swiss standard SN EN ISO 15189:2013 as a medical laboratory for pathological diagnostics.
Thank you for your trust and cooperation!

Certification specialist training pathology

The residency program at the Institute of Pathology of the University of Bern is certified by the Swiss Medical Association FMH. FMH specialist titles for pathology, neuropathology as well as subspecialty titles in cytopathology and molecular pathology can be acquired at our institute.

Colorectal cancer screening

We participate in the colorectal cancer screening programme of the Canton of Bern

Mammographie-Screening

https://www.donna-programm.ch/de/willkommenzum-donna-programm.html

5 years UCI

We have been a pathology partner of the Tumour Centre Bern UCI for 5 years.

With a hydrogel against black skin cancer

Researchers at the University of Bern have developed a therapy option that activates the body's own defense system against black skin cancer. Components of a bacterium are embedded in gel and applied directly to the area of the tumor. In the model, the gel was shown to reduce tumor growth, inhibit its spread to other organs and thereby prolong survival. In a next step, the gel will be tested for its efficacy in patients in clinical trials.

Bernese Innovation for the Pathology of the Future

Alessandro Lugli and Miryam Blassnigg from the Institute of Pathology at the University of Bern have developed a medical cockpit, called the Pathojet, which is the first of its kind in the world. In an interview, they explain the advantages the device offers for their field and their patients. Link for the Movie and Interview:

Teacher of the Year 2021

Since the past year was a special one and each medical school year underwent its own particular challenges, every class had the chance to choose a “Teacher of the Year”. We warmly congratulate Y. Banz, selected for Year 4.

Napoleon’s Cause of Death

Contribution on RTSI for the Bicentenary of Napoleon’s Death on St. Helena, May 5th 1821

Tumour budding in solid cancers

Our colorectal Cancer (CRC) research group organized in 2016 the "International Tumour Budding Consensus Conference (ITBCC)" which led to the implementation of tumour budding in the TNM/WHO classifications and in the NCCN (National Comprehensive Cancer Network), CAP (College of American Pathologists) and ESMO (European Society for Medical Oncology) guidelines as well. Our recent review published in Nature Reviews Clinical Oncology not only summarizes the clinical scenarios of tumour budding in CRC and other solid cancers, but also focuses on the molecular and biological aspects and the association with EMT (epithelial-mesenchymal transition) and TME (tumour microenvironment). Key processes involved in the tumour budding phenotype (from Lugli et al, Nat Rew Clin Oncol 2020).

Increasing the effectiveness of immunotherapy against skin cancer

Researchers at the University of Bern have discovered a mechanism in the body’s own immune system which is responsible for the maturation and activation of immune cells. In the fight against skin cancer, the results have the potential to help immunotherapies succeed, even in patients for whom they have so far been ineffective.

SBP Optima Certificate

The Optima Label (16.12.2019) demonstrates compliance with the Gold Biobanking Practices; in particular OECD Best practice guidelines for biological resource centres (2009), ISBER Best Practices (2018) and IARC Common minimum technical standards (2017). It follows established standards, including the ISO 20387:2018 - General requirements for biobanking.

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